The problem of ecological safety is getting more and more serious, all over the world and within the country. In some regions it has even reached such an extent that it has undermined the foundation for sustainable development of the social economy and agricultural production. Unfortunately academic study on regional ecological safety has not yet really started. While studying how to set up conceptual framework for selection of an indicator system for assessment of regional ecological safety, the paper puts forth an indicator system for assessment of regional ecological safety, which may be used as theoretic basis for studies on assessment of regional ecological safety and management of eco-environment.