Based on the quadrature rotary composition designing method, an experiment was conducted on effects of application of Nitrogen, Phosphate, Potassium and Zinc, respectively, on yield and quality of wheat..The Results indicate that yield is significantly and positively related to N and P application, and wet Gluten content to N, but significantly and negatively to P.,The effect of K and zn application on yield and quality of wheat is very limited.In terms of effect on yield,the four kinds of fertilizer are in a decreasing order, i.e. N > P > Zn > K, while in terms of effect on quality,the content of wet Gluten, the order is N > P > K > Zn. Analysis of the results shows that reasonable yield and quality can be obtained when the application rate of N ranges within 252.8~294.2kg/hm², of P 111.0~139.1 kg/hm²,of K 145.8~153.0 kg/hm², and of Zn 9.8~12.1kg/hm² and that a reasonal proportion of the four nutrient elements N,P₂O₅,K₂O and ZnSO₄ in formulated fertilization should be 1:0.46:0.55:0.04.