Based on analysis of mechanism of interactions between change in regional land use structures and sustainable land use, in a case study of Xishan City, trend of diversification and centralization of land use structure in the research region was analyzed and trend of changes in land use structure of Xishan City in year 2005 and 2010 and its effect on regional sustainable land use were predicted by rebuilding the Grey Systemic Dynamic Model. According to this research, the land use structure of Xishan City will show alienation of agricultural lands, degradation of agricultural land, hard-to-correct inefficiency of land use and increasing shortage of land resource reserves. Hereby, finally this paper brings forward some suggestions to advance the sustainable land use of the research region through protecting the agricultural land resource especially the resources of cultivated land, reasonably harmonizing the relationship between agricultural land and non-agricultural land, consummating the policy system for land use in the region and improving the rate of science and technology substitutinge land resource.