The characteristics of vertical variation and horizontal variation of Pb in the soil-plant system of the vertical zones in the Changbai Mountain National Nature Reserve were studied in this paper. The results showed that Pb concentrations in the soils of the vertical zones are all over 25mg/kg, and the average Pb concentration in each soil zone is negatively related to its degree of variation, i.e. in the brown coniferous forest soil zone, its average Pb concentration is the lowest of the four soil zones, but its horizontal variation the highest; whereas, in the mountain soddy forest soil, its average Pb concentration is highest, but its horizontal variation the lowest. The average Pb concentrations in plants along the vertical zones are all lower than the karat value of Pb in plant, which is basically similar to soil Pb concentration in variation. But in terms of horizontal variation,the mountain Tundra zone is the highest, while the Betula ermanii forest zone the lowest. The vertical variation of Pb concentration in plants is obviously higher than that in soils, with its variation coefficient reaching 89.76%. The enrichment capability of plants for Pb varies with the type of the plant and the organ of the plant. Parent material and parent rock, soil pH, soil organic matter and soil texture etc. are the main factors influencing variation of Pb concentration in the soil-plant system along the vertical zones in the Changbai Mountain National Nature Reserve.