This paper studied effect of salt stress on growth of cotton and effect of cultivation practices on growth and yield of cotton under salt stress. The results showed that salt stress significantly suppressed growth of cotton seedlings. In soils with salt content being 3.0g/kg leaf area and growth rate of the plants decreased remarkably, the number of bolls and boll-bearing branches reduced, yield and biomass declined. Application of organic manure improved growth of cotton seedlings, increased the number of bolls and boll-bearing branches of an individual plant, and also raised yield and biomass of the plant.