Micro-element status of tobacco soils in Southwest Hubei province was statistically analyzed. The results showed that ① 81.1% of the soils were deficient or potentially deficient in water soluble B; 60% in available Zn, 60% in available Cu and 98% in available Cl. To improve yield and quality of the tobacco crop, the fertilizers recommended for tobacco should contain the above mentioned elements. ② Soil available Mo content varied in a relatively wide range (0~3.3 mg/kg), and varied greatly across the tobacco region. Mo fertilizers should be applied according to the local soil Mo status. ③ After more than 20 years of tobacco cultivation and management, the percentage of soils deficient in Zn, Cu and B decreased by 11.5%, 25.4% and 24.2%, respectively. But no uniform law could be deduced fitting different tobacco production zones.