Factors affecting transferability of famoxadone in soil were studied with the soil column leaching method. Results showed that vertical distribution of famoxadone in the soil column varied with pesticide application rate, rainfall, precipitation intensity. The maximal leaching depth of famoxadone in the soil increased with application rate and rainfall when they were in the range from 175 μg to 700 μg and from 50 mm to 200 mm, respectively, but decreased with precipitation intensity. Surfactant contamination of the soil could affect transferability of famoxadone in the soil dramatically. Anionic surfactant (SDBS) and nonionic surfactant (Tween-80) could promote transfer of famoxadone, while cationic surfactant (CTAB) prevent using the experimental concentrations.