Land use plan is very important for regional sustainable development, and the protective index and spatial distribution of farmland are the key parts of land use plan. This paper, taking Jiangning County as the study site, with the multiple-objective programming method after establishing the models of the productive and ecological protection of farmland, economic development as well as the restrictive conditions of regional balance development, the protective index and spatial distribution of farmland were determined. The results showed that the multiple-objective programming method was effective in establishing scientifically the regional farmland retaining indexes in the land use plan of China.