Under the current situation, the conception of scientific development should be further strengthened in functional zoning for comprehensive land-use planning. In addition to stressing factors of the current land use status, it is also essential to emphasize its harmonization with socio-economic development and ecological protection, so as to maximize the comprehensive benefit of land use. Guided with the conception, the authors put forth a functional zoning index system and its quantification method for evaluating cultivated land preservation potential, economic and constructive development potential, and environment protection pontential, and define types of function zones corresponding to different combinations. And then, based on integrated consideration of various combinations of resources, and economic and ecological characters, and land use status, the authors adopted the clustering method to carry out comprehensive function zoning of land use in Yixing with town as unit. Five function zones were defined as priority development zone, moderate development zone, moderate protection zone, development prohibited zone, and grey zone. Finally, the authors analyzed characteristics of each function zone from the angle of socio-economy, and suggested direction and controlling measures of land use in Yixing.