A bacterium (AW70) capable of degrading avermectins was successfully isolated from the long-term avermectins polluted soil. This strain was identified as Burkholderia sp. based on the physiological & biochemical characteristics and homology analysis of its 16S rDNA sequence. AW70 could use avermectins as the sole-carbon source for growth and it could maintain the good degrading ability at the temperature of 25℃ ~ 42℃ and initial pH value of 6.5 ~ 8.5. The most adaptable initial pH value and temperature for the degradation of avermectins were 7.0 and 37℃ under which more than 85% of the pesticide could be degraded within 48 h. In the bioremediation of avermectins contamination on oranges in Nanfeng, Jiangxi province, AW70 could degrade 0.247 mg/kg avermectins to non-detectable level, indicating that the strain has a great potential application.