The greenhouse pot experiment was conducted to investigate the modified effects of attapulgite and Na-Montmorillonite on Cu-Zn-Cd contaminated red soil. The results showed that the above-ground biomass of ryegrass (Lolium multiflorum Lam) of the two crops significantly increased with the application of the two kinds of clays. The fresh biomass of the two crops were 7.60 g/pot and 5.67 g/pot for the CK treatment respectively, and the biomass increased by 184% and 159% with the application of 80 g/kg attapulgite, and increased by 113% and 99.3% with the application of 80 g/kg Na-Montmorillonite. Application of the two clays increased soil pH value from 0.26 units to 1.02 units, and decreased the bioavailability of Cu, Zn and Cd. Cu, Zn and Cd concentrations in the ground part of ryegrass decreased as the addition amount of the two clays increased from 20 g/kg to 80 g/kg. The reductions in Cu and Cd concentrations were in the order of Na-Montmorillonite > attapulgite, and there was no significant differences for Zn. Available Cu and Zn in the TCLP extractant solutions significantly decreased with the application of 40 g/kg and 80 g/kg attapulgite and Na-Montmorillonite, while available Cd significantly decreased only with the application of 80 g/kg attapulgite.