To study the effects of Panax notoginseng continuous cropping on P. notoginseng seed germination and seedling growth, the main germination indexes, seedling growth indexes and R/S of P. notoginseng under different soil conditions were investigated and analyzed for ANOVA using DPS7.05 software package. The results showed:①Compared with first cropping soil, the maximum germination speed of P. notoginseng in continuous cropping soil increased, and germination vigor changed little, while the germination rate, germination index and fast germination stage decreased. ②The ratio of seedling survival and plant height of P. notoginseng decreased significantly (p<0.05) with the increase of cropping year. ③ Compared to outer-rhizosphere soil (CK), rhizosphere and under-rhizosphere soils inhibited significantly P. notoginseng seed germination, but promoted aboveground biomass of P. notoginseng seedling. Germination vigor, germination rate and germination index of P. notoginseng seed in rhizosphere and under-rhizosphere soils decreased significantly compared to CK, and the maximum germination speed of P. notoginseng also decreased. There were obvious obstacle effects of continuous cropping on seed germination and seedling growth in P. notoginseng, which may be related to the allelopathy (autotoxicity).