With the incubation experiment under constant temperature and humidity, the paper studied the effects of different concentrations of urease inhibitor (NBPT), nitrification inhibitor (DMPP), and their combinations on urea nitrogen transformation in albic soil in Sanjiang Plain. The results showed that the effective time of NBPT was less than 14 days. NBPT reduced urea hydrolysis and transformation effectively, 2.5%NBPT was better than 0.5%NBPT. DMPP inhibited the transformation of ammonium nitrogen to nitrate nitrogen effectively. It also kept high level of soil NH4+-N more than 45 days in albic soil, the differences between 1%DMPP and 5%DMPP were not obvious. The combination of NBPT and DMPP was better than the treatment of only NBPT or DMPP. The treatment of 0.5%NBPT + 1%DMPP was more effective in controlling urea hydrolysis, retaining high level of soil NH4+-N.