In order to investigate nutrients in tobacco growing soils of Tongren and to provide the theoretical basis for the production of tobacco with good quality, 90 soil samples were collected and analyzed from 4 tobacco growing counties in Tongren and the methods of principal component analysis and membership function of fuzzy mathematics were used to estimate the status of soil fertility by means of estimating SFI. The results showed that pH value was slightly high. The average content of soil organic matter content was 26.1 g/kg, which was sufficient. Soil total and available N were appropriate to tobacco growth. Soil available P was high, but total P content was partial low. Soil total K was low and available K content varied widely, only 24.44% of the samples were in the suitable range (150-220 mg/kg). Soil fertility showed a big variation, soil fertility index (SFI) ranged from 0.29 to 0.94, with an average of 0.68 and the variation coefficient of 17.04%. According to the value of SFI, soil fertility was classified as 5 levels: high, less higher, middle, low and lower. Soil with fertility at high and higher grade accounted for 45.56%. Soil nutrient in Dejiang areas was higher but lower in Sinan areas. It suggested that management of soil fertility should be based on the particular site by the means of fertilization and using different fertilization prescription for different nutrients in order to improve the reasonable availability of nutrients.