The effects of the Three Gorges Project on climate change have been widely concerned as a scientific question. Meteorological factors of Zigui country in typical area of the head part of the Three Gorges Reservoir were continuously observed and analyzed from 2001 to 2010. According to the existing observation data, main meteorological factors such as temperature, rainfall, air pressure and sunshine showed a certain degree of annual fluctuations, but no significant change was found. Compared with before water storage, annual average temperature in Zigui typical area decreased by about 0.3℃, annual average highest temperature decreased by about 0.7℃, annual average lowest temperature increased by about 0.3℃; average temperature in April, May and December after water storage increased by 0.8℃-1.0℃, the other month dropped by about 0.4℃-2.0 ℃; average≥10℃ effective accumulated temperature dropped by about 116.6℃ after water storage. During the 10 years, except for a few decrease of extreme highest ground temperature, no significant change was observed in average ground temperature, the average highest ground temperature and extreme minimum temperature. April to August of every year was the most concentrated raining period. The annual average rainfall was 939.7mm from 2001 to 2010, and the highest rainfall was 1 148.7 mm in 2008, and the lowest rainfall was 742.8 mm in 2009. The annual average evaporation was 937.0 mm; average evaporation from May to September in different years was 668.5 mm, which accounting for 71.3% of the annual evaporation. Average air pressure showed an increase trend, which was 101.0 kPa in 2010 and increased by about 1.2% compared with 2001. Sunshine fluctuated and showed a general decreasing trend. The highest sunshine was 1 384.9 h in 2004 and the lowest was 981.8 h in 2005.