It is of significant to know the contents of heavy metals in the fertilizers for tobacco sustainable production. 95 fertilizer samples used in 2010 and 2011 from 12 tobacco-planting provinces of China were collected and the heavy metal contents of As, Cd, Cr, Hg and Pb in the fertilizers were analyzed. The results showed that the contents of heavy metals were lower than the national limits. The contents of Pb and Cr were high. The heavy metal contents were usually higher in phosphate fertilizers, As, Cr and Pb were higher in inorganic compound fertilizers, Hg and Cr were higher in organic fertilizers, Pb and Cd were higher in potassic fertilizers. The contents of Cd and Cr in tobacco fertilizers of Huang-Huai tobacco-planting region were higher compared with other regions.