Winter wheat-summer rice rotation is one of the general cropping systems in the Tai Lake Region, China, but which is favor ammonia (NH₃) and nitric oxide (NO) emission to atmosphere due to high N input with low N use efficiency (NUE), thus it is necessary to improve the agronomic management practices to alleviate the detrimental impacts of these gaseous compound emissions. This study is to illustrate the effectiveness of an improved integrated crop cultivation, water and nutrient practice for mitigating NH₃ and NO emissions. Dynamic and static chambers were employed to simultaneously estimate NH3 and NO emissions from a rice-wheat rotation field with three different treatments of 1) CK (control, without N input), 2) FP (the famer’s practice); and 3) IP (the improved crop cultivation, water and nutrient management practice with nitrogen dose reduced by 25% compared to FP in the Tai Lake Region. Crop yield and agronomic N use efficiency (ANUE) were appraised. In the rice-wheat rotation, the total crop yield from IP treatment was consistent with FP, and ANUE increased by 39% (P<0.05). Compared to FP, IP in the rice and wheat seasons mitigated seasonal NH₃ emissions by 26% and 44%, respectively. In meanwhile, IP emitted marginal NO (N 0.75±0.03 kg/hm²) into the atmosphere in rice growing season, which was in consistent with CK and FP. Besides, IP decreased NO emission by 49% in wheat growing season. Thus, IP practice should be advocated in this region for it sustaining crop yield and decreasing the environmental risk by mitigating significantly NH₃ and NO emissions at the same time.