Determination of basic farmland ecological risk region is important to ensure food security, sustainable economic and social development in China. Based on GIS and by using the minimum cumulative resistance model, basic farmland ecological risk region of Dongpo district in Meishan City, Chengdu plain city were evaluated. By choosing the basic farmland of Dongpo district as the ‘source’, and taking slope, land use types, distance from the main road, distance from the secondary road, distance from the river and distance from ponds as the resistance layer, minimum cumulative resistance grid point mutations as a threshold point, four function areas named as basic farmland key area, general area, transition area and non basic farmland area had been determined. Determination of basic farmland ecological risk region can provide scientific decision- making basis for the study area.