A pot experiment was conducted to study the effects of continuous peanut cropping (0, 2, 4 and 6 years) on rhizosphere soil enzyme activities, soil nutrient contents and dry matter accumulation of cultivar Guihua17 and wild variety A. correntina. The results showed that with the continuous cropping year increase, compared with the control (no continuous cropping), soil available nutrient contents and dry matter accumulation were decreased, the decline in A. correntina was lower than Guihua 17,the activities of soil urease, invertase and acid phosphatase of Guihua 17 decreased, the activities of soil urease, invertase and acid phosphatase of A. correntina at various stages changed irregularly, and little difference occurred between different treatments. The activites of soil hydrogen peroxide enzymes of the two varieties also changed irregularly. Comparatively, the changes in soil physical and chemical properties, biological properties of wild speciesA. correntina was smaller than cultivars variety Guihua 17.