It is important to explore soil pH variation and its influential factors for better crop management. In this study, a survey was conducted to obtain soil pH and the spatial parameters in Beijie of Guizhou. The spatial characteristics of soil pH was analyzed by using the methods of geostatistics and GIS. Results showed that soil pH ranged from 5.12 to 9.20. Soil pH optimal interpolation model was selected. The trend index of the model was 1, proved the model was rational. The ratio between nugget value and base value was 65.10%, showed a medium spatial dependence and suggested structural factors (the natural factors) had a greater influence on soil pH. Soil pH value showed an order of basic rocks > sand shale > fluvial deposits > carbonate rocks > purple rocks > argillaceous rocks > quartzites. Soil pH values showed were 6.29, 6.83, 7.07, 7.17 and 8.20 for limestone soil, yellow soil, yellow soil, purple soil and brown soil, respectively. The correlation analyses of soil pH with the elevation, slope, and slope aspect showed a moderate correlation, weak correlation and medium correlation, respectively. Overall, pH of arable land in Bijie is affected by both structural factors (natural factors) and human factors.