The effective utilization of straws in agriculture is attracting more and more attention. In order to solve the problem of slow degradation of straw after returning to the field, 7 strains were screened which can produce cellulase: Phomopsis liquidambari, Phoma sp., Trichoderma viride, Trichoderma reesei, Rhizopus, Aspergillus niger and Bacillus alvei. The strains were combined to make liquid agents of A ( Phomopsis liquidambari, Phoma sp., Trichoderma viride,Bacillus alvei) and C (all of the seven strains) and their corresponding solid agents of B and D. The effects of compound agents on the degradation rates of wheat straws and the improvement of soil quality were discussed. The results showed that 4 kinds of inoculants could promote the degradation of wheat straws, improve soil biological characteristics, increase soil nutrients and improve agronomic traits of maize. According to comprehensive evaluation of each index, agent B showed the best performance, and the total yield of maize was 20.72% higher than that of straw degradation agent on the market. In conclusion, the utilization of wheat straws returning to field together with combined inoculum can obviously improve the soil degradation function, it provide a promising combination method of straw degradation agent for the sustainable agricultural management.