Antibiotics, as emerging environmental pollutants, have garnered attention due to their potential impact on public health. On the one hand, numerous natural antibiotics are present in soil environments. On the other hand, the rapid growth of China's animal husbandry industry has resulted in the release of a significant amount of exogenous antibiotics and antibiotic resistance genes (ARGs) through livestock and poultry manure, which can enter the soil and ultimately threaten human health through the food chain. In recent years, China has proposed the "combination of planting and breeding" in promoting sustainable agriculture development. Incorporating organic materials is a crucial aspect of circular agriculture cultivation, enhancing soil properties, altering microbial community structure, and ultimately influencing the migration and spread of antibiotics and ARGs in soil. To examine the influence of plant-derived organic materials on ARGs diffusion in farmland soil, this article reviewed recent researches both domestically and internationally. The effect of plant-derived organic material addition on ARGs diffusion and the associated mechanism in farmland soil were explained. This review could provide a scientific basis for the resourceful use of organic materials, and enhance the risk assessment framework for antibiotic resistance genes within agricultural environments.