Based on the collation and analysis of soil pollution investigation data from 602 legacy sites of closed and relocated enterprises in the Yangtze River Delta (YRD) region, this study explored the soil pollution characteristics and corresponding management strategies for these sites across different industries. The analysis was conducted from multiple dimensions, including site hydrogeological features, spatial distribution, industrial characteristics, pollution and risk conditions, and major pollutant types. The results showed that the industries of organic chemical raw material manufacturing, metal surface treatment and heat treatment and chemical pesticide manufacturing should be paid attention to in soil environmental management. Heavy metals and organic pollutants were the main pollutants in the left plots. Benzene-series compounds, chlorinated hydrocarbons, heavy metals mercury, arsenic, lead and nickel were the most frequent pollutants in the left plots. There was an obvious relationship between soil pollutants in the left plots and the types of industries and duration of industrial utilization. Benzene-series compounds, petroleum hydrocarbons, chlorinated hydrocarbons and polycyclic aromatic hydrocarbons all had different frequencies in the left plots of chemical industry. The most frequent heavy metals of chromium and lead were in the left plots of heavy metal surface treatment and heat treatment industries and other battery manufacturing industries.