This study aims to ascertain the influence of soil salinization level on the nutrient indexes in the southern coast of Laizhou Bay. Through systematic sampling and testing, data on various indicators such as total salt content, pH, total nitrogen, total phosphorus, total potassium, and organic matter were obtained from 212 surface soil samples. The influence of soil salinization on nutrient characteristics was explored using methods such as correlation analysis and one-way ANOVA, combined with geostatistics and geographic information system technology. The results showed that the average value of soil total salt content in the study area was 0.84%, with strong spatial variability, and the overall distribution characteristics were high in north and low in south. The average value of soil pH was 8.28, mainly alkaline soil. The average values of soil total nitrogen and organic matter were in the deficiency level, while the average values of total phosphorus and total potassium were in the moderate level. The comprehensive grade of soil nutrients was mainly fourth grade, with a sample size of 64.15%. There was a significant positive correlation between the contents of various soil nutrient indexes, showing a strong spatial correlation. The soil nutrient indexes were significantly negatively correlated with total salt content, and all except for total potassium were significantly negatively correlated with soil pH. The soil nutrient indexes had the lowest content in coastal saline soil. The results of this study revealed the spatial variation characteristics of soil salinization and nutrient indicators in the southern coast of Laizhou Bay, evaluated the degree of soil salinization and nutrient levels, which can guide regional soil improvement and development.