I In this paper, the spatial distribution characteristics of soil salinity, pH value and soluble salt ions in the Keriya Oasis were analyzed using spatial autocorrelation and radial basis function interpolation method. The results showed that saline soil had a strong surface aggregation and alkalinity, and soil salt content increased gradually from south to north. The variation coefficient of soil salinity, Mg²⁺, Na⁺, Ca²⁺, K⁺ , Cl^- and SO₄^2- showed high variance, HCO₃^- showed medium variance, and pH showed low variance. The Moran’s I for soil salinity, pH and base cations were lower than 0.4, indicating these variables were low spatially clustered and autocorrelated. Strong positive correlations were observed between soil salinity and Na⁺, K⁺, Cl^-, SO₄^2- (P<0.01), indicating that saline soils are mainly composed of chlorate and sulphate. There was moderate positive correlation between soil salinity and Ca²⁺ and Mg²⁺ contents (P <0.05). Soil pH had very weak correlations with soil salinity and soluble ions. The above results provide scientific basis for the rational exploitation of water resources and the sustainable development of oasis agriculture, and are helpful to the decision support for the improvement of saline soils and the prevention and control of desertification.