To explore the effect of different sealing methods on the survival rate of tomato seedlings, three treatments of soil sealing were designed in this paper, which included the traditional soil sealing (CK), unsealed hole and sand sealed hole, and the distribution of soil water, salt and the growth of tomato seedlings were compared. The results showed that no significant difference existed between soil moistures and salt contents in different soil layers between tomato plants. Unsealed hole and sand sealed hole reduced average soil moistures of tomato root area significantly by 12.82% and 10.63% for 0-10 cm soil, 11.39% and 10.13% for 10-20 cm soil compared with those of CK, which provided suitable soil moisture for tomato seedling growth. Unsealed hole and sand sealed hole reduced average salt contents of root zone by 30.17% and 34.64% for 0-10 cm soil and 30.26% and 28.29% for 10-20 cm soil compared with those of CK, which inhibited soil salt accumulation and provided a relatively desalinated soil environment for tomato seedling growth. The growth of tomato seedlings were similar under different treatments, but unsealed hole and sand sealed hole promoted the elongation of seedling roots, significantly increased the survival rate of tomato seedlings, and increased the root depth of tomato seedlings by 13.74% and 9.16% and the survival rate by 10.36% and 11.06% compared with those of CK, thus, unsealed hole or sand sealed hole should be adopted for tomato planting in Hetao irrigation area.