A greenhouse pot experiment was conducted using Funneliformis mosseae (FM), Rhizophagus intraradices (RI), and Glomus versiforme (GV) of arbuscular mycorrhizal fungi (AMF) to reveal the effect and mechanism of AMF inoculation on Cd stress tolerant of Arundo donax. The results showed that under Cd stress, AMF inoculation significantly improved the plant growth, compared with the control, plant height increased by 19.09% - 27.98%, leaf length increased by 12.18% - 31.06%, chlorophyll content SPAD value increased by 8.55% - 9.36%, biomass of aboveground and belowground increased by 20.08% - 31.41% and 12.24% - 24.12%, maximum net photosynthetic rate increased by 7.08% - 32.12%, and P content in roots increased by 30.26% - 46.05%. After AMF inoculation, Cd content in Arundo donax was between 68 - 105.97 mg/kg, significantly higher than that of the control (42.20 mg/kg). Cd content in roots ranged from 113.07 to 221.71 mg/kg, significantly higher than the control (46.47 mg/kg). The effects of different AMF strains on plant under Cd stress were different, for example, RI treatment had the best effect on plant height and leaf length, while total N, total P, total K and Cd contents were the highest under GV treatment. This study showed that AMF inoculation under Cd stress can promote the plant growth, enhance plant photosynthesis, increase the absorption of N and P and K, and enhance plant absorption to Cd. The Arundo donax-arbuscular mycorrhizal symbiont has a potential application in remediating Cd contaminated soil.